Q&A   with

 Dr. Shingoro Matsuura

 1  What gave birth to the initial objective or the concept to develop a product like DR-XENIJI?

The initial concept of developing DR-XENIJI is to assist pregnant women and help develop healthy babies.

 2  How much time, research and capital did you use in order to develop DR-XENIJI?
I have spent 23 years on research and 3.1 billion Yen to develop DR-XENIJI.

 3  How does the fermentation process contribute to the effectiveness of DR-XENIJI?
DR-XENIJI is made from more than 50 different kinds of ingredients such as fruits and vegetables in season. While these ingredients are fermented, numerous micro-organisms work and produce new forms of "vitamins", pre-digested nutrients and amino acids during the fermentation process. To conclude, fermentation creates new, effective and powerful bioactive components that are beneficial to maintaining good health.

 4  Why is it necessary to have such a long fermentation period of 1185 days?
The reason why DR-XENIJI needs a fermentation period of 1185 days is simply my hypothesis during university days. I translated the fermentation process into the mechanism of human body. Like this illustration, the first 6 months is the medium period. It represents culturing the medium base, then 1 year for stomach period to digest ingredients into small molecules, and another year for intestines to ferment further, and the last 9 months represents the womb period. This is for maturation. 30 years ago nobody appreciated this theory, but now people love and favor DR-XENIJI. It is a very unique product.

 5  In your opinion, what is the difference between DR-XENIJI and the common enzyme products now available in the market?
Enzyme products in the market are extracts taken from fermented sugars or alcohols, so such products are fermented for only 3 to 6 months, or a year at most. On the other hand, DR-XENIJI takes a much longer time to produce effective components by fermentation.

 6  How did DR-XENIJI manage to obtain the JACT (Japanese Association for Alternative, Complementary and Traditional Medicine) certification?
DR-XENIJI is the 1st health food product to receive the JACT "reliability and safety mark". DR-XENIJI was approved because of the fact that we have been able to produce many new scientific and clinical data and have continued to supply safe and qualified products for more than 20 years.

 7  What are the criteria for JACT certification and how stringent are they?
Criteria for Certification are:

1. Safety as Food

   Suitable for everybody's consumption (from a baby to the old and the pregnant). No matter how much one eats, it will not be harmful.

2. Stabilized Supply of Ingredients

3. Quality Control of Manufacturing

4. Basic/Clinical study of Physiological Effects

The JACT Approval committee usually review and examine all submissions repeatedly under their strict guidelines until the products can satisfy and conform to all the set criteria before granting their approval.

 8  Does JACT certify the physiological effects of the certified products?
As to new clinical data reported by Dr. Yokoyama, who practices Alternative, Complementary and Traditional Medicine, DR-XENIJI is an effective health food supplement for anti-aging. DR-XENIJI can make you younger, because new cells are being produced. Many doctors who are conducting Alternative, Complementary and Traditional Medicine subscribe to DR-XENIJI, because they understand that it is effective for geriatric diseases (diseases of the elderly), other lifestyle-related diseases, and certain other various diseases.

 9  What are the clinical researches conducted on DR-XENIJI and what do the results prove?
Many clinical researches have proven that DR-XENIJI has a favorable impact on metabolism. Highlights of the proven results are as follows:

Dr. Yokoyama, Kanda Ishin Clinic, Tokyo, Japan who practices alternative medicine reported the following:

a)  DR-XENIJI can be considered as a useful health food supplement for anti-aging and longevity, because it stimulates the secretion of rejuvenating hormones such as IGF-1 and DHEA.

1GF-1 (Insulin-like growth factor-1) - hormone secreted by the liver and other tissues in response to growth hormones. It stimulates muscle and bone growth. It also has anti-aging effects.

When aged, the function of producing new cells declines. However, DR-XENIJI plays a big role in vitalizing IGF-1 (a growth factor to promote physical growth).

DHEA (dehydroepiandrosterone) - steroidal hormone secreted by the adrenal glands. It helps in slowing down aging, enhancing memory and prevention of osteoporosis. DHEA has been known among medical researchers since 1934, and is an adrenal hormone that is converted to the male hormone androgen or the female hormone estrogen. Both androgen and estrogen decline with age, but DR-XENIJI stimulates their production.

b)  DR-XENIJI stimulates the secretion of neurotransmitter dopamine, so children concentrate better and study harder. DR-XENIJI also works on Alzheimer's disease by helping to increase the secretion of dopamine.

Dopamine - neurotransmitter, a chemical messenger between nerve cells in the brain affecting brain processes that control movement, emotional response, and ability to experience pleasure and pain.

 10  How does DR-XENIJI have a favourable impact on metabolism?

Regarding the effect on metabolism, as I explained previously, DR-XENIJI plays a big role in vitalizing IGF-1, and the function to produce new cells are activated. As a result, DR-XENIJI makes you rejuvenated or makes you younger.

 11  What are the objectives of holding international symposiums and who are the people who attend them?
The purpose of holding the International Symposium is to introduce and help people obtain information on the benefits of DR-XENIJI. We have spoken about the benefits of DR-XENIJI which prevents illnesses, optimizes good health, cures the diseases taken together with medicine, etc., in front of the audiences of doctors, consumers, health advisors, etc.

 12  How does this R&D relate to the improvement of human health and in what areas?
This research definitely helped many consumers experience health improvement. In Japan, over 250 million consumers have taken DR-XENIJI, and we have received many amazing reports from them.

 13  How much have you or your company spent on R&D?
I have spent over JPY3.1 billion for my research and development. Also, I have added another JPY3 billion after finishing the development of product for clinical research, collecting scientific data, and obtaining the international patent. This research is my lifework. Therefore, I have no grudges against the expenses spent on research.